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For Sale

221 South Main St, Middleton MA 01949

Middleton, MA 01949

$1
1,820 sf · 3.05 ac · Built 2018
The residence

Excellent opportunity to lease approximately 1,820 SF of well-appointed retail/service space with direct frontage on Route 114 (South Main Street), one of the North Shore's primary commercial corridors with traffic counts exceeding 30,000 vehicles per day. Previously occupied by a boutique med spa, the space is already built out with a welcoming reception and waiting area, multiple private treatment rooms, and two bathrooms, providing an attractive opportunity for a new tenant to occupy with minimal upfront build-out. The existing layout lends itself particularly well to medical, wellness, aesthetics, professional office, and other service-oriented concepts, subject to landlord and municipal approval. The space is located within an established and highly active commercial center featuring a strong mix of national and local tenants, including Starbucks, Salem Five Bank, and Btone Fitness. This complementary tenant mix helps generate consistent daily customer traffic and makes the center a well-known destination along the Route 114 corridor. The property offers excellent visibility and exposure along Route 114, convenient customer and employee parking in the shared on-site lots, and signage opportunities, including an available panel on the property's street pylon sign.

At a glance
Property type
Residential
Status
Active
Year built
2018
Lot size
3.05 acres
Living area
1,820 sf
MLS#
51344f0e3dfed4eaa5759426b37f4740
Beds · Baths
0 · 0
Estimated Monthly Payment+
$0/mo
Approximate · principal & interest only
Display Currency
$1

Indicative conversion — settlement always in USD.

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Listing courtesy of Five Mark Realty Group LLC · MLSPIN

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Listings updated Sep 3, 2026

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