6,769± SF second-floor office opportunity featuring three distinct suites available for lease together, ideal for a company seeking a dedicated headquarters with separate offices, departments, or functional workspaces. The existing layout offers flexibility for professional services firms, training organizations, administrative operations, and other businesses requiring multiple separate spaces under one lease. Convenient elevator access and a functional multi-suite configuration provide a versatile opportunity for a variety of business uses. Each suite features its own restroom, with an additional common-area restroom available. The building also offers elevator access for added convenience. Neighboring tenants include Dunkin’, D’Angelo, and Descar Jewelers.
49 River St, Waltham MA 02453
Waltham, MA 02453
- Property type
- Commercial Lease
- Status
- Active
- Year built
- 1900
- Lot size
- 2.85 acres
- MLS#
- e65e7f7efdff2191c5c4263afb584bfb
- Beds · Baths
- 0 · 0
Waltham, MA.
Waltham, Massachusetts, is a market our advisors follow closely — its streets, housing stock and setting each shape what a residence here is worth and how it lives day to day. We are glad to walk you through the locale in detail, and how this particular address sits within it.
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Listings updated Oct 16, 2026



